DocumentsDate added
Case report
Amrit Kaur Kaler1*, Roopa AN.2, Subramanyam H2,
Shameem Shariff3, & Kusuma4
Affiliation:-
*1Assistant Professor of Pathology,2Associate Professor of Pathology,3Professor of Pathology, 4Post graduate student, MVJ Medical College & Research Hospital, Bangalore, Karnataka, India. 560029.
Abstract:
Complex Fibroadenoma (CF) is a subtype of fibroadenoma harbouring one or more complex features, including epithelial calcifications, papillary apocrine metaplasia, sclerosing adenosis, and cysts larger than 3 mm. These neoplasms tend to occur in the older patients. CF is usually smaller than a fibroadenoma and represents a degenerative change over a period of years. A case of CF is reported in which the mass was hard and gritty on cut section, measuring 7x6x6 cms, involving the entire breast and mimicking a carcinoma. The present case is reported in order to make the pathologists aware of this variant and to emphasize that complex fibroadenoma should be considered in differential diagnosis of breast lesions as it carries 3.1 times higher risk of malignancy as compared to the general population. This article also emphasizes on the various patterns seen on complex fibroadenoma. Also proposed are the follow up criteria for the management of these patients.
Key Words: Complex Fibroadenoma; neoplasms, malignancy.
References:-
1.Radswiki et al. Complex fibroadenoma. Radiopedia.com.
2.Kuijper A, Mommers EC, van der Wall E, van Diest PJ. Histopathology of fibroadenoma of the breast. Am J Clin Pathol 2001; 115: 736 -42.
3.Dupont WD, Page DL, Parl FF et al. Long-term risk of breast cancer in women with fibroadenoma. N Engl J Med 1994; 331: 10 -15.
4.Carter BA, Page DL, Schuyler P, et al. No elevation in long-term breast carcinoma risk for women with fibroadenomas that contain atypical hyperplasia. Cancer 2001; 92: 30-6.
5.Miri Sklair-Levy, Tamar Sella, Tanir Alweiss, Ilia Craciun, Eugene Libson, Bella Mally. Incidence and Management of Complex Fibroadenomas. Am J Roentgenol. 2008; 190(1):214-8.
6.Gordon PB, Gagnon FA, Lanzkowsky L. Solid breast masses diagnosed as fibroadenoma at fine-needle aspiration biopsy: acceptable rates of growth at long-term follow-up. Radiology 2003; 229: 233-8.
7.Stacey E. Mills. Sternberg’s Diagnostic Surgical Pathology.4th edition, Volume 1. Lippincott Williams & Wilkins, Philadelphia, PA, USA, 2004.
8.John P. Sloane. Biopsy pathology of the Breast. Second edition. Oxford University Press Inc., New York. 2001 Arnold.
9.Foster MC, Helvie MA, Gregory NE, Rebner M, Nees AV, Paramagul C. Lobular carcinoma in situ or atypical lobular hyperplasia at core-needle biopsy: is excisional biopsy necessary? Radiology 2004; 231: 813-9.
Article citation:-
Amrit Kaur Kaler, Roopa AN, Subramanyam H, Shameem Shariff, & Kusuma. Complex fibroadenoma: A most neglected variant of fibroadenoma. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) 2013 May (Supplement 1); 30(30): S36-S39. Available at http://www.jpbms.info
Copyright © 2013 Amrit Kaur Kaler, Roopa AN.,Subramanyam H,Shameem Shariff, & Kusuma. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Review article
Ravleen Kaur1, Inderjot Singh2, Gina Singh3, Anushi Mahajan4
Affiliation:-
1Assistant Professor, Department of Periodontics, Christian Dental College, Ludhiana, Punjab, India.
2Associate Professor, Department of Oral & Maxillofacial surgery, Christian Dental College, Ludhiana, Punjab, India.
3Professor and Head, Department of Periodontics, Christian Dental College, Ludhiana, Punjab, India.
4Assistant Professor, Department of Periodontics, Christian Dental College, Ludhiana, Punjab, India.
*Correspondence to:-
Dr Ravleen Kaur
Assistant Professor, Department of Periodontics,
Christian Dental College, Ludhiana, Punjab, India
Phone no:- +91-09781108811
Abstract:
Dental professionals have addressed the increased challenge of infectious disease and infection control by emphasizing seven major areas; aseptic technique, patient screening and evaluation, personal protection, instrument sterilization, environmental surface disinfection, equipment asepsis and laboratory asepsis. Each infection control component contributes to minimizing the potential for cross-infection during provision of dental treatment. Dental patients fall into several risk categories concerning the transmission of infection. Some patients will only suffer from dental or oral diseases, others are infected, some are healthy carriers, and yet others are symptomatic or asymptomatic carriers of a transmissible disease at a contagious or noncontiguous stage.
Key words: Periodontal aerosol; dental aerosol; bioaerosols.
References:
1.Legnani P, Checchi L, Pelliccioni GA, D’Achille C. Atmospheric contamination during dental procedures. Quintessence Int 1994 Jun; 25:435–9.[Pubmed]
2.Leggat PA, Kedjarune U. Bacterial aerosols in the dental clinic: a review. Int Dent J 2000; 51:39-44.[Pubmed]
3.ADA Council on Scientific Affairs and ADA Council on Dental Practice. Infection control recommendations for the dental office and the dental laboratory. J Am Dent Assoc 1996;127:672–80.[Pubmed]
4.John A. Molinari, Gail E. Monilari. Is mouthrinsing before dental procedures worthwhile? J Am Dent Assoc 1992; 123:75-80. [Pubmed]
5.Robet J. Ceisel, Edward M Osetek, Donald W Turner, Patricia GS. Evaluating chemical inactivation of viral agents in handpiece splatter. J Am Dent Assoc 1995; 126:197-202.[Pubmed]
6.Abel C, Miller RL, Micik RE, Ryge G. Studies on dental aerobiology. Part IV. Bacterial contamination of water delivered by dental units. J Dent Res 1971; 50:1567-9.[Pubmed]
7.Bagga B, Murphy R, Anderson A, Punwani I. Contamination of dental cooling water with oral microorganisms and its prevention. J Am Dent Assoc 1984; 109:712-6.[Pubmed]
8.King TB, Muzzin KB, Berry CW, et al. The effectiveness of an aerosol reduction device for ultrasonic scalers. J Periodontol 1997;68:45-9.[Pubmed]
9.Checchi L, Matarasso S, Pirro P, D Achille C. Topograghical analysis of facial areas most susceptible to infection with transmissible diseases in dentists. Int J Periodontics Restorative Dent 1991; 11:164-72.[Pubmed]
10.Nicholas LP, George HW, Donald ES, Charles EB. Laminar air purge of microorganisms in dental aerosols. JADA 1970;81:1131-4.
11.Miller LR, Mick RE, Abel C, Ryge G. Studies on Dental Aerobiology: II. Microbial splatter discharged from the oral cavity of dental patients. J Dent Res 1971;50:621-5. [Pubmed]
12.Larato DC, Ruskin PF, Martin A, Delanko R. Effect of Dental Air Turbine Drill on Bacteria count in Air. J Prostho Dent 1966;16:758-5.
13.Harrel SK, Barnes JB, Rivera-Hidalgo. Aerosol and splatter contamination from the operative site during ultrasonic scaling. J Am Dent Assoc 1998;129:1241-9.[Pubmed]
14.Micik RE, Miller RL, Mazzarella MA, Ryge G. Studies on dental aerobiology:I. Bacterial aerosols generated during dental procedures. J Dent Res 1969;48:49-56.[Pubmed]
15.Wirthlin MR, Choi JH, Kye SB. Use of chlorine dioxide mouthrinse as the ultrasonic scaling lavage reduces the viable bacteria in the generated aerosols. Periodontal abstracts 2006;54:35-43. [Pubmed]
16.Miller LR, Mick RE. Air pollution and its control in dental office. Dent Clin N Am 1978;22:453-76.[Pubmed]
17.Grundy JR. Enamel aerosols created during use of the air turbine handpiece. J Dent Res 1967;45:409-16.[Pubmed]
18.Kazantis G. Air contamination from high speed dental drills. Proc Roy Soc M ed 1961;54:242-4.[Pubmed]
19.Day CJ, Sandy JR, Ireland AJ. Aerosols and Splatter in dentistry- A Neglected menace? Dent Update 2006;33:601-6.[Pubmed]
20.Belting CM, Haberfelde GC, Juhl LK. Spread of organisms from dental air rotor. J Am Dent Assoc 1964;68:648-51.[Pubmed]
21.Bennett AM, Fulford MR, Walker JT, Bradshaw DJ, etal. Microbial aerosols in general dental practice.Br Dent J 2000;189(12):664-7.[Pubmed]
22.Pelleu GB, Shreve WB, Wachtel LW. Reduction of microbial contamination in the air of dental operating rooms:I.High-efficiency particulate airfilters. J Dent Res 1970;49:315-22.[Pubmed]
23.Veksler AE, Kayrouz GA, Newman MG. Reduction of salivary bacteria by pre-procedural rinses with chlorhexidine 0.12%. J Periodontol 1991; 62:649-1.[Pubmed]
24.Barnes JB, Harrel SK, Rivera-Hidalgo. Blood contamination of the aerosols produced by an invivo use of ultrasonic scalers. J Periodontol 1998; 69:434-8.[Pubmed]
25.Toroglu MS, Bayramoglu O, Yarkin F, Tuli A. Possibility of blood and hepatitis B contamination through aerosols generated during debonding procedures. Angle Orthod 2003;73:571-8.[Pubmed]
26.Li RW, Leung KW, Sun FC, Samaranayake LP. SARS (Severe acute respiratory syndrome) and the GDP. Part II: Implications for GDPs. Br Dent J 2004;14;197:130-4.[Pubmed]
27.Grenier D. Quantitative analysis of bacterial aerosols in two different clinic environments. Appl Environ Microbiol 1995;61:3165-8.[Pubmed]
28.Bentley CD, Burkhart NW, Crawford JJ. Evaluating spatter and aerosol contamination during dental procedures. J Am Dent Assoc 1994; 125: 579–4. [Pubmed]
29.Larato DC, Ruskin PF, Martin A. Effect of an ultrasonic scaler on bacterial counts in air. J Periodontol 1967;38:550-4.[Pubmed]
30.Fine DH, Mendieta C, Barnett ML, Furgang D, Meyers R, Oslshan A, Jack V. Efficacy of preprocedural rinsing with an antiseptic in reducing viable bacteria in dental aerosols. J Periodontol 1992; 6:821-4.[Pubmed]
31.Williams GH, Pollok NL, Shay DE, Barr CE.Laminar air purge of microorganisms in dental aerosols. Prophylactic procedures with the ultrasonic scalers. J Dent Res 1970;49:1498-04.[Pubmed]
32.Cochran MA, Miller CH, Sheldrake MA. The efficacy of the rubber dam as a barrier to the spread of micro-organisms during dental treatment. J Am Dent Assoc 1989;119:141-4.[Pubmed]
33.Logothetis D, Jean M. Reducing bacterial aerosol contamination with the chlorhexidine gluconate pre-rinse. J Am Dent Assoc 1995;126:1634-9.[Pubmed]
34.Micik RE, Miller RL, Leong AC. Studies on dental aerobiology: III. Efficacy of surgical masks in protecting dental personnel from airborne bacterial particles. J Dent Res 1971; 50:626-30.[Pubmed]
Article citation:-
Ravleen Kaur, Inderjot Singh, Gina Singh, Anushi Mahajan. Aerosols a menace for the dental healthcarers. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) May(Supplement 1); 30(30):S58-S62. Available at http: //www.jpbms.info.
Copyright © 2013 Ravleen Kaur, Inderjot Singh, Gina Singh, Anushi Mahajan. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Original article:
*1Harsha T R, 2Vijaya D & 3Nagarathnamma T
Affiliations:
1Assistant professor, Department of Microbiology, Victoria hospital, Bangalore Medical College, Bangalore, Karnataka, India.
2Professor and Head, Department of Microbiology, Adichunchangiri Institute of Medical Sciences, Karnataka, India.
3Professor and Head, Department of Microbiology, Bangalore Medical College, Karnataka, India.
Abstract:
Background and objective: Urinary tract infections (UTI) are the most common bacterial infections and account for significant morbidity and health care costs. Antibiotics are usually prescribed empirically before the laboratory results of urine culture are available. Due to rising antibiotic resistance among uropathogens, it is important to have local hospital based knowledge of the organisms causing UTI and their antibiotic sensitivity patterns. This information would be relevant not only to the local hospital but would also be a vital regional database.
Methods: A total of 600 urine samples from suspected cases of UTI referred from various departments of Bowring & Lady Curzon Hospital formed the study group. Samples are subjected to microscopy and culture. Isolates were identified by a battery of biochemical tests. Conventional method of antibiotic susceptibility was done by Kirby Bauer disc diffusion method and Rapid method by Mini API.
Results: UTI’s were more common in the age group of ≤10 years (24.16%) and in females (53.44%). 32.6% cases were from the inpatients and 67.4% from outpatient departments. Out of 600 cases studied, 69 cases (11.5%) yielded significant bacteriuria. Escherichia coli was the most common uropathogen isolated (73.9%) followed by Klebsiella spp (24.6%), and Citrobacter spp (1.4%). E. coli was 100% sensitive to amikacin and imipenem and highly resistant to ampicillin (19.6%), norfloxacin (15.6%). Klebsiella spp were highly sensitive to imipenem (100%) and piperacillin/tazobactum (82.3%) and resistant to ampicillin (5.8%), cefotaxime (17.6%). Citrobacter spp was sensitive to imipenem alone. Antibiotic susceptibility pattern obtained by conventional method is in correlation with the rapid method (MINI API).
Conclusion: The rapid method for antibiotic susceptibility testing by Mini API is technically simple, reliable (results are similar to disk diffusion method), early reporting (within 48 hours), and cost effective.
Key Words: Urinary tract infection; E.coli; Mini API.
References:
1.Tambekar DH, Dhanorkar DV, Gulhane SR, Khandelwal VK, Dunhane MN. Antibacterial susceptibility of some urinary tract pathogens.Afr J Biotechnol 2006 Sep;5(17):1562-5.
2.Joseph O Ehinmidu. Antibiotics susceptibility patterns of urine bacterial isolates. Trop J Pharmaceutical Res 2003 Dec;2(2):223-8.
3.Gupta V, Yadav A, Joshi RM. Antibiotic resistance patterns in uropathogens. Indian J Med Microbiol 2002;20:96-8.
4.Anbumani N, Mallika M. Antibiotic resistance pattern in uropathogens in a tertiary care hospital. Indian J Prac Doc 2007 nov;4(1):3-4.
5.Irene E Dyer, Timothy M Sankary, Jo Ann Dawson.Antibiotic resistance in bacterial UTI’s. West J Med 1998;169: 265-8.
6.KatarzynaHryniewicz, KatarzynaSzczypa,AgnieszkaSulikowska, Krzysztof Jankowski, KatarzynaBetlejewska,WaleriaHryniewicz. Antibiotic susceptibility of bacterial strains isolated from UTI’s in . J AntimicrobChemother 2001;47:773-80.
7.SemraKurutepe, SuheylaSurucuoglu, CenkSezgin, HoruGazi, Mehmet Gulay, BerilOzbakkaloglu. Increasing antimicrobial resistance in Escherichia coli isolates from community acquired UTI. Jpn J Infect Dis 2005;58:159-61.
8.Azra S Hasan, Nair D, Kaur J, Baweja G, Deb M, Aggarwal P. Resistance patterns of urinary isolates in a tertiary Indian hospital. J Ayub Med Coll Abbottabad 2007;19(1).
9.National Committee for Clinical Laboratory Standards. Performance Standards for Antimicrobial Susceptibility testing 2002 January;22(1).
10.Gayral JP, Albertini MT, Gallice E, Marcel JP, Carret G, Flandrois JP. Rapid ATB: A new system for rapid susceptibility testing of bacteria. Recent advances in chemotherapy 1985:440-1.
11.Mohammed akram, Mohammed Shahid, Asad-U-Khan. Etiology and antibiotic resistance patterns of community acquired UTI’s. Ann ClinMicrobiolol 2007;6:4.
12.Nwanze PI, Nwaru LM, Oranusi S, Dimpka U, Okwu MU, Babatunde BB et al. Prevalence and antibiotic susceptibility pattern of UTI. Sci Res essay 2007 April;2(4):112-6. 13.Anthony J Schaeffer. Infections of the urinary tract.Cambell’s Urology.8th ed., Philadelphia: Saunders, 2002.
14.Dimitrov TS, Udo EE, Emara M, Awni F, Passadilla R. Etiology and antibiotic susceptibility patterns of community acquired UTI’s. Med Prince Pract 2004;13:334-9.
15.HadizaHima-Lerible, Didier Menard, AntoTalamin. Antimicrobial resistance among uropathogens that cause community acquired UTI’s. J AntimicrobChemother 2002 Dec;51(1):192-4.
16.Yvonne Vasquez, W Lee Hand. Antibiotic susceptibility patterns of community acquired UTI’s. J Applied Res 2004;4(2).321-6.
17.Mohabbed H Abu Setteh. Uropathogens and their susceptibility pattern.Gulhane Tip Dergisi 2004;46(1):10-14.
Copyright © 2013 Harsha T R. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Research article:
*1G.Sasikala, 2David Agatha, 3Anand B Janagond & 4P.R.Thenmozhivalli
Affiliation:-
1Assistant professor, Department of microbiology, Vinayaka missions Kirupananda Variyar Medical College, Seeragapadi, Salem- 636308.Tamilnadu, India.
2Assistant professor, Department of microbiology, Madras Medical college. Chennai,India.
3Assistant professor, Department of microbiology,Sri Muthukumaran Medical college and Research institute, Chennai, Tamilnadu, India
4 Dean,Villupuram, Medical college, Villupuram, Tamilnadu, India.
Abstract :
Background: To study the prevalence of vaginal candidiasis and to speciate the Candida isolates and to study the resistance pattern for fluconazole, itraconazole and 5 flucytosine. Materials and methods: High vaginal swabs obtained from 200 symptomatic patients were subjected to direct microscopy and culture. Speciation was done by standard morphological and biochemical tests. Antifungal susceptibility was performed according to CLSI M44-A document using fluconazole, itraconazole and 5flucytosine disks. Result: The culture was positive in 72 (36%) patients. C.albicans (35), C.glabrata (21), C.tropicalis (8), C.krusei (4), C.kefyr (2), C.Parapsilosis (2), were the species isolated .The isolates showed 19%, 24%, 42% resistance to fluconazole, itraconazole and 5flucytosine respectively. C.krusei was resistant to all drugs. Low socioeconomic status, illiteracy chronic antibiotic use, parity>2 influence increased prevalence of vaginal candidiasis. Conclusion: C.albicans is the most predominant species isolated and among non-albicans, C.glabrata is the next most common species isolated. Our study showed a low prevalence of fluconazole resistance in C.albicans, but high prevalence of azoles resistance in non albicans Candida isolates. High prevalence of primary resistance to 5 flucytosine seen in our population. There is a significant association between socioeconomic status, literacy, parity and the increased incidence of vaginal candidiasis.
Key Words: Candida species; azoles resistance; primary resistance to 5 flucytosine.
References:-
1.Ferrer J. Vaginal candidosis. Epidemiological and etiological factors. Intl J Gynecol Obstet 2000; 71: S21-7.
2.Srujana Mohanty et al.Prevalence and susceptibility to fluconazole of candida species causing valvovaginitis. IJMR Sep 2007; 126: 216 – 19.
3.Saporiti AM: Vaginal candidiasis. Etiology & sensitivity profile to antifungal agents in clinical use .Rev Argent Microbiol 2001 Oct – Dec; 33 (4): 217-22.
4.MC Millan.Clinical practice in sexually transmitted diseases 2002: 497.
5.Whelan, W.L. and D.Kerridge 1984. Decreased activity of UMP pyrophosphorylase associated with resistance to 5 – fluorocytosine in candida albicans. Antimicrob. Agents chemother .26:570-574.
6.Chander J.Candidiasis.A textbook of medical mycology.2ndedition.2002:p.212-30.
7.Clinical Laboratory standards Institute: 2002 .Method for antifungal disk diffusion susceptibility testing in yeasts. Approved guideline, vol.M44-A CLSI, wayne, pa.
8.Omar AA et al.Gram stain versus culture in diagnosis of VVC. East mediterr Health J 2001 Nov; 925-34. 50.
9.Jindal et al. An epidemiological study of VVC in women of child bearing age. IJMM 2007.
10. Odds FC. Candidosis of genitalia. Candida and candidosis. A review and Bibliography, 2nd edn. London, Philadelphia, Toronto 1988 p. 124.
11.Goldacre MJ, watt B, Loudon N, Milne LJ, London JD, Vessey MP Vaginal Microbial flora in normal young women. Br. Med J 1979; 1; 1450-15.
12.Gultekin B et al. Distribution of candida Sp in vaginal specimen and evaluation of CHROM agar candida .Mikrobiyol Bul 2005 Jul: 39 (3); 319-24.
13.Buscemi L, Arechavala A, Negroni R. (study of acute vulvovaginitis in sexually active adult women, with special reference to candidosis in patients of the Francisco J. Muniz Infectious Diseases Hospital Rev. Iberoam Micol 2004; 21:177-181.
14.Sojakova et al. Fluconazole and itraconazole susceptibility of vaginal yeast isolates from slovakia. Mycopathologia 2004.
15.Arzeni D et al. Prevalence and antifungal susceptibility of vaginal yeasts in outpatients attending a gynaecological centre in Ancona, Italy. Eur. J Epidemiol 1977 Jun ; 13(4) 447-50.
16.Willinger B et al. Evaluation of CHROM agar candida for rapid screening of clinical specimens. for candida species.Mycoses 1999: Apr ; 42 (1-2).
17.Momani OM et al. Cost effectiveness and efficacy of CHROM agar candida medium in clinical specimen. East Mediterr health J 2000; 6(5-6); 968-78.
18.Pirotta MV, Gunn JM, chondros P. ''Not thrush again!'' women's experience of post-antibiotic vulvovaginitis. Med J Aust 2003; 179:43-6.
19.Richter SS, Heilmann KP, Coffman SL, Huynh HK, Brueggemann AB, Pfaller MA, et al. The molecular epidemiology of penicillin-resistant Streptococcus pneumoniae in the United States, 1994–2000. Clin Infect Dis. 2002;34:330–9. doi: 10.1086/338065.
20.R. L. Stiller, J. E. Bennett, H. J. Scholer, M. Wall, A. Polak and D. A. Stevens.The Journal of Infectious Diseases Vol. 147, No. 6 (Jun., 1983), pp. 1070-1077.
Copyright © 2013 Sasikala G., Agatha David, Janagond B Anand, Thenmozhivalli P.R. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Case report:-
Archana Wankhade1*,Dnyaneshwari Ghadage2, Arvind Bhore2& Shripad Bhat3
Affiliation:-
*1Assistant Professor, 2Professor, Department of Microbiology, 3Associate Professor, Department of Medicine Smt Kashibai Navale Medical College and Hospital, Narhe, Pune-411041,India.
Abstract:
Tuberculosis is a generalized disease most commonly localized in the pulmonary system. Chronic disseminated tuberculosis is defined as the disease prolongs and involves several organs of the body. Rarely there may be Chronic dissemination of tuberculosis in various extrapulmonary sites for which culture is required for firm diagnosis.
Case:- A 23 year old thin build female patient visited the OPD to rule out the cause of infertility. The patient had past history of tuberculosis for which the treatment had been completed. After diagnostic laproscopy, ascitic fluid was submitted in Microbiology. Mycobactererium tuberculosis was isolated by Bact/Alert 3D and antitubercular drug sensitivity was done by proportion method. The patient was treated with CAT II drugs under RNTCP. With the gap of 6 months the patient presented with cervical lymphadenopathy and pleural effusion. Lymph node biopsy tissue was sent in Microbiology laboratory for the Mycobacterial culture. Mycobacterium tuberculosis was isolated by Bract/Alert 3D automated system. Both the specimens were negative for culture on LJ by conventional method.
In conclusion, our patient presented with a group of uncommon extrapulmonary presentation including abdominal involvement with associated cervical lymphadenopathy without any immunodeficiency context but not responding to antitubercular drugs. The firm diagnosis was made by culture.
Key words: Dissiminated TB, extrapulmonary TB.
References:
1.Sharma, S.K., Mohan, A., Prasad, K.L., et al. Clinical profile, laboratory characteristics and outcome in miliary tuberculosis. QJM 1995; 88:29-37.
2.Stephanie C. Andres, M.D. and Angeles Tan-Alora, A Case Series on Disseminated Tuberculosis Phil J Micro Infect Dis 2001; 30(1):29-35.
3.Verver S,Warren R,Richardson M,Spuy G,Martien W,Borgodorff,E .Donald. Rate of reinfection tuberculosis after successful treatment is higher than rate of new tuberculosis. Am J. Resp. Crit. Care. Med 2005; 171 (12):1430-5.
4.Richardson M,Carroll N ,Erica E ,Spuy G, Salker F, Munch Z, Multiple mycobacterium tuberculosis Micro strains in early cultures from patients in high incidence communbiol 2002;40(8):2750-4.
Article citation:-
Archana Wankhade, Dnyaneshwari Ghadage, Arvind Bhore & Shripad Bhat. Chronic disseminated tuberculosis: A case report. Journal of pharmaceutical and biomedical sciences (J Pharm Biomed Sci.) 2013 May (Supplement 1); 30(30): S28-S30.Available at http://www.jpbms.info
Copyright © 2013 Archana B Wankhade. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.